Perfusion imaging uses an intravascular tracer and serial imaging to quantify blood flow through the brain parenchyma. In acute ischemic stroke, perfusion imaging may increase diagnostic accuracy, aid treatment target identification, and provide prognostic information about functional outcome.
Does CT perfusion rule out stroke?
Its early diagnosis is important as its treatment is dependent on the time elapsed since ictus. Delay in diagnosis and treatment translates into increase neuronal loss and thereby increased morbidity. CT scan, and in particular perfusion CT, has helped greatly in the early diagnosis of stroke.
How does stroke relate to perfusion?
Within six hours of stroke onset approximately 70% of acute patients will have a perfusion volume greater than the diffusion volume, 20% will have equal volumes, and in 10% the perfusion volume will be smaller, representing spontaneous reperfusion.
What is the best imaging for stroke?
Currently in the United States, noncontrast computed tomography (CT) remains the primary imaging modality for the initial evaluation of patients with suspected stroke (Figure 1).
What scan shows blood flow to the brain?
Computed tomography (CT) perfusion imaging shows which areas of the brain are adequately supplied or perfused with blood and provides detailed information on delivery of blood or blood flow to the brain. CT perfusion scanning is a noninvasive medical test that helps physicians diagnose and treat medical conditions.
What is CT brain perfusion scan?
How CT perfusion is done?
Perfusion CT is performed by monitoring only the first pass of an iodinated contrast agent bolus through the cerebral circulation (,23).
What is perfusion of the brain?
A brain perfusion scan is a type of brain test that shows the amount of blood in certain areas of your brain. This can help show how your brain is functioning. The areas of the brain that are very active often show greater blood supply, oxygen supply, and use of glucose.
How is CT perfusion imaging used in acute stroke?
CT Perfusion Imaging in Acute Stroke Computed tomographic perfusion (CTP) imaging is an advanced modality that provides important information about capillary-level hemodynamics of the brain parenchyma.
How is the treatment of acute stroke determined?
Therapy for acute stroke depends on ensuring the diagnosis and excluding diseases that mimic cerebral ischemia, such as hypoglycemia, hyponatremia, a seizure, or a mass lesion such as a tumor or subdural hematoma. The exclusion of a hemorrhagic rather than ischemic stroke can be determined rapidly and accurately with CT or MR imaging.
What kind of imaging is used for perfusion?
Finally, with the evolution of helical and spiral multislice CT technology, CT perfusion (CTP) imaging is becoming a potentially important clinical technique. 10 Although the development of these technologies has been fascinating, their role in evaluating a variety of diseases of the CNS is controversial.
How is the volume of brain tissue measured in CT perfusion?
The volume of brain tissue included in a first pass cine perfusion CT study is constrained in the craniocaudal direction by the width of the CT detector. Hence, the z-axis coverage of each acquisition depends on the manufacturer and generation of the CT scanner.