How common is statin induced myopathy?

1 About 1.5-3% of statin users in randomised controlled trials and up to 10-13% of participants enrolled in prospec- tive clinical studies develop myalgia. 1-4 As a conserva- tive estimate, at least 1.5 million people per year will experience a muscle related adverse event while taking a statin.

What percent of patients taking statins will experience myopathy?

Conclusion. Statins play a vital role in the prevention of atherosclerotic cardiovascular complications, and statin therapy continues to be a mainstay in treating patients with dyslipidemia. However, statin-associated myopathy affects up to 10% of patients receiving statin therapy.

How long does statin induced myopathy last?

For most patients, myopathy symptoms induced by statin therapy resolve relatively quickly; however, the results of the PRIMO study showed that it may take up to 2 months for resolution of symptoms.

What does statin-induced myopathy feel like?

Symptoms of statin-induced myopathy Common complaints, especially in the lower body, include: cramps. heaviness. stiffness.

How is statin-induced myopathy treated?

Currently, the only effective treatment of statin-induced myopathy is the discontinuation of statin use in patients affected by muscle aches, pains and elevated CK levels.

What does statin induced myopathy feel like?

How do you manage statin myopathy?

Coenzyme Q10 and vitamin D have been used to prevent and treat statin myopathy; however, clinical trial evidence demonstrating their efficacy is limited. Statin-intolerant patients may be successfully treated with either low-dose statins, alternate-day dosing, or using twice-weekly dosing with longer half-life statins.

What does statin myopathy feel like?

How long does it take to recover from statin-induced myositis?

The majority of muscle damage by statins is secondary to its direct toxic effects, possibly via coenzyme Q10 depletion causing mitochondrial dysfunction. The injury is dose dependent and reversible after withdrawing the drug, with most recovery of symptoms occurring within 2–3 months (3).