Can oral KAYEXALATE be given rectally?

It can be administered orally or rectally as an enema. One gram of KAYEXALATE contains 4.1 mEq of sodium. KAYEXALATE is a non-absorbed, cation exchange polymer that contains a sodium counterion.

How do you give Kalimate?

・Your dosing schedule prescribed by your doctor is<< to be written by a healthcare professional>> ・In general, for adults, take 15 to 30 g a day in two to three divided doses. Add a dose to 30 to 50 mL of water, stir up and take it. The dosage should be adjusted according to your symptoms.

Why is KAYEXALATE given with sorbitol?

Background: Kayexalate (sodium polystyrene sulphonate) in sorbitol is commonly used to treat hyperkalemia in patients with renal insufficiency. Isolated case reports and one recent large series have documented intestinal necrosis following administration of kayexalate in sorbitol.

How do you administer sodium polystyrene sulfonate enemas?

Use sodium polystyrene sulfonate rectally as an enema as directed by your doctor, usually every 6 hours as needed. Keep the enema in the rectum for several hours, if possible. Use a non-sodium-containing cleansing enema after each dose as directed.

Can KAYEXALATE be given daily?

The average total daily adult dose of KAYEXALATE is 15 g to 60 g, administered as a 15-g dose (four level teaspoons), one to four times daily.

What medication is used for hyperkalemia?

Patients with hyperkalemia and characteristic ECG changes should be given intravenous calcium gluconate. Acutely lower potassium by giving intravenous insulin with glucose, a beta2 agonist by nebulizer, or both. Total body potassium should usually be lowered with sodium polystyrene sulfonate (Kayexalate).

Does KAYEXALATE cause edema?

Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: muscle weakness/spasms, fast/irregular heartbeat, mental/mood changes (such as irritability, confusion, slowed thinking), swelling hands/ankles/feet.

What are the side effects of KAYEXALATE?

Common side effects of Kayexalate include:

loss of appetite,
upset stomach,
nausea,
vomiting,
constipation, or.
diarrhea.

When should you not use KAYEXALATE?

KAYEXALATE is contraindicated in the following conditions: patients with hypokalemia, patients with a history of hypersensitivity to polystyrene sulfonate resins, obstructive bowel disease, neonates with reduced gut motility (postoperatively or drug induced) and oral administration in neonates (see PRECAUTIONS).

When should you not give KAYEXALATE?

What can you mix with Kayexalate?

KAYEXALATE powder is usually given by mouth mixed in a small amount of water. It can also be mixed with food or some sweetened liquid Do NOT mix KEYEXALATE with orange juice or fruit juice which contains potassium.

How much water to mix with Kayexalate?

You can mix the Kionex ( Kayexalate) with about 100 cc of water. The exact amount is not actually critical, aside from making it more palatable. It is often given with sorbitol also to make it more palatable.

When to give Kayexalate for high potassium?

Kayexalate is indicated for the treatment of hyperkalemia. Kayexalate should not be used as an emergency treatment for life-threatening hyperkalemia because of its delayed onset of action [ see Clinical Pharmacology (12.2)]. Administer Kayexalate at least 3 hours before or 3 hours after other oral medications .

How does Kayexalate lower potassium?

Kayexalate increases fecal potassium excretion through binding of potassium in the lumen of the gastrointestinal tract. Binding of potassium reduces the concentration of free potassium in the gastrointestinal lumen, resulting in a reduction of serum potassium levels.