Mifepristone is taken as a single 600 mg (i.e. 3 tablets of 200 mg each) oral dose, followed 36 to 48 hours later, by the administration of the prostaglandin analogue gemeprost 1 mg per vaginam.
When should I take mifegyne?
Mifegyne is recommended to be used: 1) For the medical termination of a pregnancy: – no later than 63 days after the first day of your last menstrual cycle, – in combination with a second medicine, a prostaglandin (a substance that triggers contraction of the womb and softens the cervix), which you take 36 to 48 hours …
What happens after taking Mifegyne?
After taking the Mifegyne® tablet nothing much will happen for about 12 hours. After 12 hours you may start to bleed. Though do not worry if there is no bleeding.
What drug class is mifepristone?
Mifepristone is in a class of medications called antiprogestational steroids. It works by blocking the activity of progesterone, a substance your body makes to help continue pregnancy.
How long is mifepristone in your system?
Following a distribution phase, elimination of mifepristone is slow at first (50% eliminated between 12 and 72 hours) and then becomes more rapid with a terminal elimination half-life of 18 hours.
What to do if you take too many Mifegyne tablets?
Only limited data is available on the use of Mifegyne in adolescents. If you take too many tablets, contact your doctor immediately or go to the nearest hospital casualty department. The doctor will give you the exact amount of Mifegyne; it is therefore unlikely that you will take too many tablets.
When to take prostaglandin after taking mifegyne?
Check with your doctor or pharmacist if you are not sure. –– Take the prostaglandin analogue, 36 – 48 hours after Mifegyne. The prostaglandin is either given as tablets which should be swallowed with water (misoprostol 400 micrograms) or as a vaginal pessary (gemeprost 1 mg).
How long do you stay at rest after taking mifegyne?
1) At the prescribing centre you will be given Mifegyne, which must be taken orally. 2) 36 – 48 hours after this the prostaglandin analogue will be administered. You should stay at rest for 3 hours after having the prostaglandin analogue.
How long after taking mifegyne can you terminate a pregnancy?
Mifegyne can therefore cause termination of pregnancy. It can also be used to soften and open the entrance (the cervix) to the womb (uterus). to 48 hours after taking Mifegyne. 2) For softening and opening of the cervix before surgical termination of pregnancy during the first trimester.