Is desmoplastic melanoma the same as spindle cell melanoma?

Formally, the diagnostic categories in these overtly spindled melanomas are: spindle cell melanoma when the collagen content is <10%, mixed spindle/desmoplastic melanoma when collagen content is 10–90%, and desmoplastic melanoma when the collagen content is >90%.

Is spindle cell cancer curable?

Spindle cell carcinoma (SCC) is a highly malignant pulmonary sarcomatoid carcinoma. There is no standard treatment for this disease, though chemotherapy, surgery and radiation therapy may be considered.

Is spindle cell carcinoma a melanoma?

Spindle cell melanoma (SCM) is a rare subtype of malignant melanoma composed of spindled neoplastic cells arranged in sheets and fascicles (1). The diagnosis of SCM is challenging, as SCM may occur anywhere on the body and frequently mimics amelanotic lesions, including scarring and inflammation (2–4).

What does spindle cell melanoma look like?

Features of spindle cell melanoma under microscopy include: An abundance of spindle-shaped tumour cells (> 90% of a tumour) Uniform, wavy, and slender nuclei, with variable size and shapes (pleomorphism) and variable nuclear atypia (abnormal appearance of cell nuclei)

What cancers have spindle cells?

Spindle cell carcinoma, also termed carcinosarcoma, pseudosarcoma, polypoid carcinoma, sarcomatoid carcinoma, and spindle cell variant of squamous cell carcinoma, is a rare type of malignant tumor that often grows as an exophytic polypoid lesion (see also Chapter 20).

How aggressive is spindle cell carcinoma?

Spindle cell carcinoma (SpCC) is an uncommon aggressive biphasic malignancy that has the propensity to manifest itself in the upper aerodigestive tract, including the oral mucosa.

What is the treatment for spindle cell sarcoma?

The usual treatment for spindle cell sarcoma is surgery to remove the tumour. Chemotherapy can be used in certain situations and we will discuss this with you we feel this is a suitable option.

How common is spindle cell sarcoma?

Spindle cell sarcoma is a soft-tissue tumour which can start in the bone. Spindle cell sarcomas of the bone are often found in the arms, legs and pelvis. They most commonly arise in patients over the age of 40 and are extremely rare, making up just 2-5% of all primary bone cancer cases.

What is a spindle cell?

Definition of spindle cell : a fusiform cell (as in some tumors) : a spindle-shaped cell (as in some tumors)

Is melanoma the only serious type of skin cancer?

Melanoma , the most serious type of skin cancer, develops in the cells (melanocytes) that produce melanin – the pigment that gives your skin its color. Melanoma can also form in your eyes and, rarely, in internal organs, such as your intestines. May 21 2019

What is spindle carcinoma?

Spindle cell carcinoma. Spindle cell carcinoma is a type of cancer that begins in the skin or in tissues that line or cover internal organs and that contains long spindle-shaped cells. It is also called sarcomatoid carcinoma.